Author

A. Necsulea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:bulk RNA-seq· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

F. Benitiere· 2 shared L. Duret· 2 shared A. Laverre· 1 shared C. K. Ng· 1 shared E. Tannier· 1 shared F. Darbellay· 1 shared M. H. Heim· 1 shared P. Veber· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

F. Benitiere

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Author profile →

5 papers

Recent·Most cited

GTDrift: A resource for exploring the interplay between genetic drift, genomic and transcriptomic characteristics in eukaryotes

F. Benitiere, L. Duret, A. Necsulea

GTDrift provides a resource analyzing genetic drift and genomic/transcriptomic features across 1,506 eukaryotic species, including life history traits, dN/dS ratios, and processed RNA-seq data for comparative studies.

bioRxiv · Jan 23, 2024Evolutionary Biology

Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

F. Benitiere, A. Necsulea, L. Duret

The paper investigates the relationship between genetic drift and mRNA splicing accuracy across metazoans, finding a negative correlation between population size and splicing rates.

bioRxiv · Dec 9, 2022Evolutionary Biology

LncRNA analyses reveal increased levels of non-coding centromeric transcripts in hepatocellular carcinoma

A. Necsulea, P. Veber, T. Boldanova, C. K. Ng, S. Wieland, M. H. Heim

The paper analyzes lncRNA expression in HCC to identify differentially expressed transcripts and reveals increased non-coding centromeric transcripts in advanced-stage tumors.

bioRxiv · Mar 3, 2021 · PreprintCancer Biology

Long-range promoter-enhancer contacts are conserved during evolution and contribute to gene expression robustness

A. Laverre, E. Tannier, A. Necsulea

The paper compares promoter-enhancer contacts in mouse and human to show evolutionary conservation and its role in gene expression robustness.

bioRxiv · Feb 26, 2021Evolutionary Biology

Comparative transcriptomics analyses across species, organs and developmental stages reveal functionally constrained lncRNAs

F. Darbellay, A. Necsulea

The paper compares lncRNA expression across species, organs, and developmental stages, finding that functionally constrained lncRNAs are enriched in developing tissues.

bioRxiv · Apr 14, 2019Evolutionary Biology