Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails
Y. Peng, S. Li, A. Onufriev, D. Landsman, A. R. Panchenko
The paper uses molecular dynamics simulations to study how histone tails modulate nucleosome DNA accessibility and protein binding, revealing distinct binding modes and competitive interactions.
bioRxiv · Oct 30, 2020Biophysics