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A. Ooishi

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Biophysics· 1

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Approach:experimental assay· 1

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H. Imamura· 1 shared S. Honda· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiophysics

H. Imamura

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BiophysicsThe Journal of Physical Chemistry LettersPeer-reviewedApr 24, 2023

Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies

H. Imamura, A. Ooishi, S. Honda

This study shows that acid denaturation of IgG1 antibodies leads to compaction, reducing their size and suggesting non-canonical structures may have biological significance.

DOI 10.1021/acs.jpclett.3c00258

experimental assay