Chimeric antigen receptors that trigger phagocytosis
M. A. Morrissey, A. P. Williamson, A. M. Steinbach, E. W. Roberts, N. Kern, M. B. Headley, R. D. Vale
This paper introduces CAR-Ps, chimeric antigen receptors that direct macrophages to engulf specific targets like cancer cells, showing over 40% reduction in cancer cell numbers in co-culture.
bioRxiv · May 16, 2018Cell Biology