Preclinical evaluation of pharmacological inhibition of SIRT1 on the growth of tumoral and metastatic granulosa cells
V. Cluzet, E. Airaud, M. M. Devillers, F. Petit, A. Leary, A. Pierre, H. Li, C.-P. Day, U. Weyemi, S. Chauvin, C. Guigon
This study evaluates SIRT1 inhibition's effect on granulosa cell tumor growth and metastasis using in vitro and in vivo models, finding reduced tumor progression with EX-527 treatment.
bioRxiv · Jul 2, 2024 · PreprintCancer Biology