Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF
V. Gorbovytska, S.-K. Kim, F. Kuybu, M. Götze, D. Um, K. Kang, A. Pittroff, L.-M. Schneider, A. Leitner, T.-K. Kim, C.-D. Kuhn
This study identifies the molecular mechanism by which eRNAs stimulate Pol II pause release by interacting with NELF through unpaired guanosines.
bioRxiv · Apr 25, 2021Biochemistry