Author

A. Pokhrel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:E. coli· 2 Organism:human· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. Söderström· 3 shared I. G. Duggin· 2 shared A. Bergenstrale· 1 shared A. Cain· 1 shared A. Costas· 1 shared A. Oludiran· 1 shared A. Poudel· 1 shared C. Abell-King· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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3 shared papersMicrobiology

B. Söderström

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

E. coli division machinery drives cocci development inside host cells

A. Pokhrel, A. Costas, M. Pittorino, I. G. Duggin, B. Söderström

This study shows uropathogenic E. coli forms cocci inside host cells through FtsZ-driven division, revealing a new level of bacterial morphological plasticity.

bioRxiv · Apr 8, 2024 · PreprintMicrobiology

The 3'UTR of vigR is required for virulence in Staphylococcus aureus and has expanded through STAR sequence repeat insertions

D. G. Mediati, W. Dan, D. Lalaouna, H. Dinh, A. Pokhrel, T. P. Stinear, A. Cain, J. J. Tree

This study identifies the 3'UTR of vigR as critical for virulence in S. aureus, showing it regulates cell wall metabolism and interacts with mRNAs involved in virulence and antibiotic tolerance.

bioRxiv · May 16, 2023 · PreprintMicrobiology

Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli

E. Westlund, A. Bergenstrale, A. Pokhrel, U. Skoglund, H. Chan, D. O. Daley, B. Söderström

The paper demonstrates live-cell single-molecule imaging of the Z-ring in E. coli using nanotags and nanobodies, achieving PALM images with fluorescent protein fusions.

bioRxiv · Feb 19, 2023 · PreprintMicrobiology

Bacterial multispecies invasion of human epithelial bladder cells

C. Abell-King, A. Pokhrel, S. Rice, I. G. Duggin, B. Söderström

This study investigates bacterial multispecies invasion of bladder cells using co-infection models and high-resolution imaging, finding that Gram-negative bacteria are more invasive and exhibit filamentation during dispersal.

bioRxiv · Feb 16, 2023 · PreprintMicrobiology

Unique features of magic spot metabolism in Clostridioides difficile

A. Poudel, A. Pokhrel, A. Oludiran, E. J. Coronado, K. Alleyne, M. M. Gilfus, R. K. Gurung, S. B. Adhikari, E. B. Purcell

The paper identifies unique mechanisms of pGpp synthesis in C. difficile's magic spot metabolism, distinct from other organisms.

bioRxiv · Aug 2, 2021 · PreprintMicrobiology