Author

A. Polyzou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

A. G. Tzioufas· 2 shared C. Kittas· 2 shared D. Veroutis· 2 shared K. Evangelou· 2 shared S. Havaki· 2 shared A. Cavazza· 1 shared A. Kotsinas· 1 shared A. Papaspyropoulos· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

A. G. Tzioufas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Senescent cells in Giant Cell Arteritis have inflammatory phenotype participating in tissue injury via IL-6 dependent pathways

D. Veroutis, O. D. Argyropoulou, A. V. Goules, K. Kambas, D. A. Palamidas, K. Evangelou, S. Havaki, A. Polyzou, E. Xingi, E. Karatza, B. A. Kyriaki, A. Cavazza, C. Kittas, D. Thanos, C. Ricordi, , A. G. Tzioufas

This study identifies senescent cells in Giant Cell Arteritis (GCA) arteries with an inflammatory phenotype linked to IL-6 dependent pathways contributing to tissue injury.

bioRxiv · May 19, 2023 · PreprintCell Biology

SARS-CoV-2 infects lung epithelial cells and induces senescence and an inflammatory response in patients with severe COVID-19

K. Evangelou, D. Veroutis, P. G. Foukas, K. Paschalaki, N. Lagopati, M. Dimitriou, A. Papaspyropoulos, O. Hazapis, A. Polyzou, S. Havaki, A. Kotsinas, C. Kittas, A. G. Tzioufas, L. de Leval, D. Vassilakos, , V. Gorgoulis

This study shows SARS-CoV-2 infects alveolar type-2 cells in severe COVID-19 patients, inducing senescence and proinflammatory cytokine expression.

bioRxiv · Jan 2, 2021 · PreprintCell Biology

ADA2 is a lysosomal DNase regulating the type-I interferon response

O. K. Greiner-Tollersrud, M. Krausz, E. Bartok, V. Boehler, H. Ebersbach, S. Baash, D. Guerini, G. Hartmann, K. Huebscher, G. Kochs, M. Marchant, A. Polyzou, J. Schepp, M. Seidl, C. R. Smulski, , M. Proietti

The paper identifies ADA2 as a lysosomal DNase that regulates the type-I interferon response by degrading cGAS/Sting-activating ligands in DADA2 patients.

bioRxiv · Jun 21, 2020 · PreprintImmunology