LRBA balances antigen presentation and T-cell responses via autophagy through the binding to PIK3R4 and FYCO1
E. Sindram, M. C. Deau, L. A. Ligeon, P. Sanchez-Martin, S. Nestel, S. Jung, S. Ruf, P. Mishra, M. Proietti, S. Guenther, K. Thedieck, E. Roussa, A. Rambold, C. Muenz, C. Kraft, , L. Gamez-Diaz
This study identifies LRBA's role in balancing antigen presentation and T-cell responses by interacting with PIK3R4 and FYCO1 to regulate autophagy.
bioRxiv · Oct 17, 2022 · PreprintImmunology