ARPC5 deficiency leads to severe early onset systemic inflammation and early mortality
E. Sindram, A. Caballero-Oteyza, N. Cogata, S. C. M. Huang, Z. Alizadeh, L. Gamez-Diaz, M. R. Fazlollahi, X. Peng, B. Grimbacher, M. Way, M. Proietti
This study identifies ARPC5 deficiency as a cause of severe early-onset systemic inflammation and early mortality in humans and mice.
bioRxiv · Jan 19, 2023Immunology