A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine-dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke
J. Ramirez-Sanchez, A. Rex, S. McCann, D. Schulze, M. Wong-Guerra, L. A. Fonseca-Fonseca, E. Garcia-Alfonso, A. Ramirez-Abreu, R. Limonta, M. Dopatka, L. Mosch, Y. Nunez-Figueredo, U. Dirnagl
This paper reports a two-center preclinical trial of JM-20, a benzodiazepine-dihydropyridine hybrid, showing modest neuroprotective effects in some rodent models of ischemic stroke but not in others.
bioRxiv · Mar 8, 2024 · PreprintPharmacology & Toxicology