Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.
Y.-T. Lin, S. Chiweshe, D. McCormick, A. Raper, A. Wickenhagen, V. R. DeFilippis, E. Gaunt, P. Simmonds, S. J. Wilson, F. Grey
This study shows HCMV evades ZAP detection by suppressing CpG dinucleotides in its IE1 gene, and TRIM25 regulates ZAP isoform expression.
bioRxiv · Jan 7, 2020Microbiology