Acute hyperoxia improves spinal cord oxygenation and circulatory function following cervical spinal cord injury in the rat
Journal of Physiological Investigation · Feb 16, 2024Peer-reviewedPhysiology
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Y.-T. Lin
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2019-2024 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship7 papers
Recent·Most cited
CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy
C. Sharp, B. H. Thompson, T. J. Nash, O. Lee, R. M. Pinto, L. Thorley, Y.-T. Lin, S. Sives, H. Wise, S. M. R. Clohisey, F. Grey, L. Vervelde, P. Simmonds, P. Digard, E. R. Gaunt
This paper engineers an influenza A virus with increased CpG content, showing it is attenuated in mice but replication competent in vaccine propagation systems, suggesting a new strategy for live attenuated vaccines.
bioRxiv · Apr 29, 2022Microbiology
Cell-free, methylated DNA in blood samples reveals tissue-specific, cellular damage from radiation treatment
M. E. Barefoot, N. Loyfer, A. J. Kiliti, M. O. Schmidt, S. Shabi-Porat, S. Jain, S. M. Roth, A. P. McDeed, N. Shahrour, E. Ballew, Y.-T. Lin, H.-H. Li, A. D. Mays, S. Rudra, A. T. Riegel, , A. Wellstein
This study uses cell-free methylated DNA in blood to detect tissue-specific damage from radiation treatment in mice and cancer patients.
bioRxiv · Apr 12, 2022Cancer Biology
Jaagsiekte sheep retrovirus infection induces changes in microRNA expression in the ovine lung
M. Contreras Garcia, A. E. Karagianni, D. Vasoya, S. Jayaraman, Y.-T. Lin, A. R. Wood, M. Dagleish, C. Cousens, M. Watson, F. Grey, D. J. Griffiths
This study identifies differentially expressed microRNAs in JSRV-infected ovine lung, showing upregulation of miR-182, miR-183, miR-96, and miR-135b, which are associated with oncogenic pathways in human lung cancer.
bioRxiv · Oct 27, 2021 · PreprintMicrobiology
Segmentation boosting with compensation methods in optical coherence tomography angiography images
Y.-C. Lee, J.-J. Ding, L. Yeung, T.-W. Lee, C.-J. Chang, Y.-T. Lin, R. Y. Chang
This study introduces a novel method to improve blood vessel detection in OCT angiography images by compensating for motion artifacts using a modified U-Net architecture.
bioRxiv · Aug 20, 2020 · PreprintBioengineering
Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.
Y.-T. Lin, S. Chiweshe, D. McCormick, A. Raper, A. Wickenhagen, V. R. DeFilippis, E. Gaunt, P. Simmonds, S. J. Wilson, F. Grey
This study shows HCMV evades ZAP detection by suppressing CpG dinucleotides in its IE1 gene, and TRIM25 regulates ZAP isoform expression.
bioRxiv · Jan 7, 2020Microbiology
RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence
C.-C. Lin, N. Mabe, Y.-T. Lin, W.-H. Yang, X. Tang, L. Hong, T. Sun, T.-P. Yao, J. Alvarez, J.-T. Chi
This study identifies RIPK3 upregulation in recurrent breast tumors, showing it promotes proliferation but also creates dependence on cystine, offering new therapeutic targets.
bioRxiv · Jun 21, 2019Cancer Biology