PKM2-mediated epigenetic reprogramming regulates hypoxic expression of PFKFB3 to promote breast cancer progression
M. R. Pandkar, A. Raveendran, K. Biswas, S. A. Mutnuru, J. Mishra, A. Samaiya, S. K. Sharan, S. Shukla
This study identifies PKM2's role in hypoxic breast cancer by regulating PFKFB3 expression through epigenetic reprogramming and HIF-1/HIF-2 interactions.
bioRxiv · Nov 6, 2022Cancer Biology