Author

A. Reifs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

R. Perez-Jimenez· 2 shared A. Diaz· 1 shared A. Fernandez· 1 shared A. Fernandez-Calvo· 1 shared A. L. Cortajarena· 1 shared A. Quesada-Ganuza· 1 shared A. Sanchez-Mejias· 1 shared B. Alonso-Lerma· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

R. Perez-Jimenez

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2 papers

Recent·Most cited

The Strongest Protein Binder is Surprisingly Labile

A. Fernandez-Calvo, A. Reifs, L. Saa, A. L. Cortajarena, D. De Sancho, R. Perez-Jimenez

The paper investigates the mechanical strength of ClfA, a bacterial adhesin, and finds it is not inherently strong without its human target.

bioRxiv · Feb 18, 2024Biophysics

Evolution of CRISPR-associated Endonucleases as Inferred from Resurrected Proteins

B. Alonso-Lerma, Y. Jabalera, M. Morin, A. Fernandez, S. Samperio, A. Quesada-Ganuza, A. Reifs, S. Fernandez-Penalver, Y. Benitez, L. Soletto, J. A. Gavira, A. Diaz, W. Vranken, B. P. Kleinstiver, A. Sanchez-Mejias, , R. Perez-Jimenez

This study resurrects ancient CRISPR-Cas9 nucleases to show their greater flexibility in PAM and gRNA requirements and their evolution toward double-strand break activity.

bioRxiv · Mar 30, 2022Evolutionary Biology