Author

A. Rosales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

A. Asokan· 1 shared A. Benkert· 1 shared A. C. Palmer· 1 shared A. C. Ramon· 1 shared A. Hillsley· 1 shared A. Mitchell-Dick· 1 shared B. Sewell· 1 shared C. O. Crosby· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBioengineering

A. Asokan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing

D. N. Fiflis, N. Rey, H. V. Lavanya, B. Sewell, A. Mitchell-Dick, S. Milo, K. Clements, A. Benkert, A. Rosales, S. Fergione, A. Asokan

This study repurposes CRISPR-Cas13 systems to enable trans-splicing of exogenous RNA fragments into endogenous pre-mRNA, improving editing of large mRNA segments in mammalian cells.

bioRxiv · Feb 6, 2024Bioengineering

Gene Expression Profiling Unveils the Temporal Dynamics of CIGB-300-Regulated Transcriptome in AML Cells

D. Vazquez-Blomquist, A. C. Ramon, M. Rosales, G. V. Perez, A. Rosales, D. Palenzuela, Y. Perera, S. E. Perea

This study uses microarray profiling to analyze the time-dependent gene expression changes in AML cell lines treated with CIGB-300, identifying modulated genes and pathways involved in apoptosis, cell cycle, and inflammation.

bioRxiv · Mar 6, 2023 · PreprintCancer Biology

Crosslinker Structure Modulates Bulk Mechanical Properties and Dictates hMSC Behavior on Hyaluronic Acid Hydrogels

L. D. Morton, D. A. Castilla Casadiego, A. C. Palmer, A. Rosales

This paper shows that the structure of peptoid crosslinkers affects hydrogel stiffness and influences hMSC behavior, with stiffer crosslinkers increasing modulus and modulating cell morphology and IDO production.

bioRxiv · Aug 3, 2022Bioengineering

Quantification of iPSC-derived vascular networks in novel phototunable angiogenic hydrogels

C. O. Crosby, A. Hillsley, S. Kumar, S. H. Parekh, A. Rosales, J. Zoldan

This paper develops a tunable hydrogel for iPSC-derived vascular network formation and shows that stiffness modulation affects vascular growth.

bioRxiv · Aug 25, 2020 · PreprintBioengineering