Increased Histone-DNA Complexes and Endothelial-Dependent Thrombin Generation in Severe COVID-19
B. A. Bouchard, C. Colovos, M. Lawson, A. Sackhiem, K. J. Mould, W. J. Janssen, M. J. Cohen, D. Majumdar, K. Freeman
This study finds elevated histone-DNA complexes and altered thrombin generation in severe COVID-19 patients, with endothelial-dependent thrombin generation contributing to coagulopathy.
bioRxiv · Jul 3, 2021Biochemistry