Author

B. A. Bouchard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

D. Majumdar· 2 shared K. Freeman· 2 shared A. M. Sackheim· 1 shared A. Sackhiem· 1 shared C. Colovos· 1 shared J. E. Boyson· 1 shared J. Li· 1 shared K. J. Mould· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

D. Majumdar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The polyanionic drug suramin neutralizes histones and prevents endotheliopathy

N. Villalba, A. M. Sackheim, M. A. Lawson, L. Haines, Y. L. Chen, S. K. Sonkusare, Y.-T. Ma, J. Li, D. Majumdar, B. A. Bouchard, J. E. Boyson, M. E. Poynter, M. T. Nelson, K. Freeman

This paper shows suramin neutralizes histones, preventing endothelial damage and improving vascular function in inflammatory conditions.

bioRxiv · Dec 9, 2021Immunology

Increased Histone-DNA Complexes and Endothelial-Dependent Thrombin Generation in Severe COVID-19

B. A. Bouchard, C. Colovos, M. Lawson, A. Sackhiem, K. J. Mould, W. J. Janssen, M. J. Cohen, D. Majumdar, K. Freeman

This study finds elevated histone-DNA complexes and altered thrombin generation in severe COVID-19 patients, with endothelial-dependent thrombin generation contributing to coagulopathy.

bioRxiv · Jul 3, 2021Biochemistry