CD4 binding-site antibodies induced by a subtype B HIV-1 envelope trimer
A. Schorcht, T. L. G. M. van den Kerkhof, J. Torres, E. Schermer, C. LaBranche, I. Bontjer, M. Brinkkemper, N. Gulzar, A. X. Han, J. Burger, G. Ozorowski, J. Scott, H. Schuitemaker, D. Montefiori, M. van Gils, , R. W. Sanders
This study shows that immunization with native-like HIV-1 subtype B Env trimers can induce CD4bs-directed broadly neutralizing antibodies in rabbits.
bioRxiv · Mar 23, 2022 · PreprintImmunology