The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1
B. Haddad Derafshi, T. Danko, S. Chanda, P. Batista, U. Litzenburger, Q. Y. Lee, Y. H. Ng, A. Sebin, H. Y. Chang, T. C. Sudhof, M. Wernig
This study identifies CHD8 as a chromatin activator in human neurons that depends on the ERK-MAPK pathway effector ELK1 for its function.
bioRxiv · Nov 10, 2020Cell Biology