The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1
R. Ernst, M. Gecht, S. Fischer, A. Seybert, A. S. Frangakis, E. Stelzer, R. Covino, G. Hummer, H. F. Hofbauer
This study identifies an amphipathic helix in Opi1 that selectively binds phosphatidic acid over phosphatidylserine, revealing lipid headgroup selectivity in membrane recognition.
bioRxiv · Jan 18, 2018Biochemistry