Identification of an anti-CRISPR protein that inhibits the CRISPR-Cas type I-B system in Clostridioides difficile
P. Muzyukina, A. Shkaruta, N. M. Guzman, J. Andreani, A. L. Borges, J. Bondy-Denomy, A. Maikova, E. Semenova, K. Severinov, O. SOUTOURINA
This study identifies AcrIB2, an anti-CRISPR protein from a C. difficile phage that inhibits the type I-B CRISPR-Cas system, showing that a partial cas operon is sufficient for interference.
bioRxiv · May 22, 2023 · PreprintMicrobiology