Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe
F. Ouasti, M. Audin, K. Freon, J.-P. Quivy, M. Tachekort, E. Cesard, A. Thureau, V. Ropars, P. F. Varela, G. Moal, I. Soumana-Amadou, A. Uryga, P. Legrand, J. Andreani, R. Guerois, , F. Ochsenbein
This study identifies how disordered regions and folded modules in SpCAF-1 from S. pombe enable histone deposition by mediating interactions with histones and PCNA during DNA replication.
bioRxiv · Jun 2, 2023Biochemistry