Kinome-centric pharmacoproteomics identifies signaling pathways underlying cellular responses to targeted cancer drugs
M. Golkowski, H.-T. Lau, M. Chan, H. Kenerson, V. N. Vidadala, A. Shoemaker, D. J. Maly, R. S. Yeung, T. S. Gujral, S.-E. Ong
The paper develops a kinome-centric pharmacoproteomics platform to identify signaling pathways and biomarkers predicting cancer drug responses and resistance in hepatocellular carcinoma.
bioRxiv · Nov 20, 2019Cancer Biology