Live biotherapeutic throat spray for respiratory virus inhibition and interferon pathway induction
I. Spacova, I. De Boeck, E. Cauwenberghs, L. Delanghe, P. A. Bron, T. Henkens, A. Simons, I. Gamgami, L. Persoons, I. Claes, M. F. L. van den Broek, D. Schols, P. Delputte, S. Coenen, V. Verhoeven, S. Lebeer
This paper develops a live biotherapeutic throat spray containing lactobacilli that inhibit respiratory viruses and induce interferon pathways in human cells and volunteers.
bioRxiv · Jan 25, 2022Microbiology