Author

A. Soliman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kortholt· 1 shared C. J. Gloeckner· 1 shared D. Chatterjee· 1 shared E. J. Kennedy· 1 shared E. Jiang· 1 shared E. Pardon· 1 shared E. R. Chan· 1 shared E. Störmer· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Kortholt

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2 papers

Recent·Most cited

A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis

G. Luo, H. Kumar, K. Alridge, S. Rieger, E. Jiang, E. R. Chan, A. Soliman, H. Mahdi, J. J. Letterio

The paper defines a core NRF2 gene set from transcriptomic data that predicts drug resistance and poor cancer prognosis across multiple cancer types.

bioRxiv · Apr 20, 2023Cancer Biology

Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2

R. K. Singh, A. Soliman, G. Guaitoli, E. Störmer, F. von Zweydorf, T. Dal Maso, L. Van Rillaer, S. H. Schmidt, D. Chatterjee, E. Pardon, S. Knapp, E. J. Kennedy, J. Steyaert, F. W. Herberg, A. Kortholt, , W. Versees

This study identifies and characterizes Nanobodies that modulate LRRK2 activity through non-ATP-competitive mechanisms, offering new tools for Parkinson's disease research and therapy.

bioRxiv · Aug 30, 2021Biochemistry