Mechano-epigenetic regulation of extracellular matrix homeostasis via Yap and Taz
D. L. Jones, R. N. Daniels, X. Jiang, R. C. Locke, M. K. Evans, E. D. Bonnevie, A. Srikumar, M. P. Nijsure, J. D. Boerckel, R. L. Mauck, N. A. Dyment
The paper shows that mechanical tension regulates tendon cell function through Yap/Taz by modulating chromatin accessibility and catabolic gene expression.
bioRxiv · Jul 11, 2022 · PreprintCell Biology