Bacterial Microbiome and Host Inflammatory Gene Expression in Foreskin Tissue
B. S. Maust, S. Petkov, C. Herrera, C. Feng, B. P. Brown, L. Lebina, D. Opoka, A. Ssemata, N. Pillay, J. Serwanga, P. Seatlholo, P. Namubiru, G. Odoch, S. Mugaba, T. Seiphetlo, , the CHAPS team
The paper analyzes the foreskin microbiome and host gene expression in adolescents from South Africa and Uganda, finding no treatment effect on bacterial communities but inverse correlations between bacterial abundance and inflammatory gene expression.
bioRxiv · Aug 29, 2022Microbiology