Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies
S. W. Yee, A. Stecula, H.-C. Chien, L. Zou, E. V. Feofanova, M. van Borselen, K. W. K. Cheung, N. A. Yousri, K. Suhre, J. M. Kinchen, E. Boerwinkle, R. Irannejad, B. Yu, K. M. Giacomini
The paper identifies SLC22A24 as a transporter for steroid conjugates and bile acids, linking genetic variants to steroid levels and disease.
bioRxiv · May 23, 2019Pharmacology & Toxicology