Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine
A. Golebiewska, A.-C. Hau, A. Oudin, D. Stieber, Y. A. Yabo, V. Baus, V. Barthelemy, E. Klein, S. Bougnaud, O. Keunen, M. Wantz, A. Michelucci, V. Neirinckx, A. Muller, T. Kaoma, , S. P. Niclou
This study shows that glioma PDOX models accurately represent patient tumors and can predict treatment responses in personalized medicine.
bioRxiv · Apr 24, 2020Cancer Biology