Liver lipophagy ameliorates nonalcoholic steatohepatitis through lysosomal lipid exocytosis
Y. Minami, A. Hoshino, Y. Higuchi, M. Hamaguchi, Y. Kaneko, Y. Kirita, S. Taminishi, A. Taruno, M. Fukui, A. Zoltan, S. Matoba
This study identifies lipophagy as a therapeutic approach to prevent NASH progression by promoting lysosomal lipid exocytosis and reducing intracellular fatty acid accumulation.
bioRxiv · Feb 22, 2022 · PreprintCell Biology