The adiponectin analogue ALY688-SR attenuates diaphragm fibrosis, atrophy and mitochondrial stress in a mouse model of Duchenne muscular dystrophy
C. A. Bellissimo, S. Gandhi, L. N. Castellani, M. Murugathasan, L. J. Delfinis, A. Thuhan, M. C. Garibotti, Y. Seo, I. A. Rebalka, G. Sweeney, T. J. Hawke, A. A. Abdul-Sater, C. G. Perry
This paper shows that ALY688-SR reduces diaphragm fibrosis and atrophy in DMD mice by lowering mitochondrial stress, but not in tibialis anterior.
bioRxiv · May 22, 2023 · PreprintPhysiology