Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development
K. J. Alfson, Y. Goez-Gazi, M. Gazi, Y.-L. Chou, N. A. Niemuth, M. E. Mattix, H. Staples, B. Klaffke, G. F. Rodriguez, P. Escareno, C. Bartley, A. Ticer, E. A. Clemmons, J. W. Dutton, A. Griffiths, , R. Carrion
This study characterizes the disease course in cynomolgus macaques infected with Sudan virus to evaluate its suitability as a model for filovirus countermeasure development under the FDA Animal Rule.
bioRxiv · May 4, 2022Microbiology