Author

J. W. Dutton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:non-human primate· 2 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Antanasijevic· 1 shared A. E. Goodroe· 1 shared A. Griffiths· 1 shared A. Ticer· 1 shared A. Ward· 1 shared B. E. Griffith· 1 shared B. Klaffke· 1 shared C. Bartley· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

A. Antanasijevic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates

Y.-N. Zhang, J. Paynter, A. Antanasijevic, J. D. Allen, M. Eldad, Y.-Z. Lee, J. Copps, M. Newby, L. He, D. Chavez, P. Frost, A. E. Goodroe, J. W. Dutton, R. Lanford, C. Chen, , J. Zhu

Glycan trimming of HIV-1 Env immunogens improves vaccine-induced neutralizing antibody responses in small animals and primates.

bioRxiv · Jul 1, 2022Microbiology

Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting

L. N. Scotten, R. Siegel, D. J. Blundon, M.-A. Deutsch, T. R. P. Martin, J. W. Dutton, E. M. Kolahdouz, B. E. Griffith

The paper links predicted blood shear forces during prosthetic valve closure to thrombogenicity, providing a metric to optimize valve designs for reduced thrombogenicity.

bioRxiv · Jun 23, 2022 · PreprintBioengineering

Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development

K. J. Alfson, Y. Goez-Gazi, M. Gazi, Y.-L. Chou, N. A. Niemuth, M. E. Mattix, H. Staples, B. Klaffke, G. F. Rodriguez, P. Escareno, C. Bartley, A. Ticer, E. A. Clemmons, J. W. Dutton, A. Griffiths, , R. Carrion

This study characterizes the disease course in cynomolgus macaques infected with Sudan virus to evaluate its suitability as a model for filovirus countermeasure development under the FDA Animal Rule.

bioRxiv · May 4, 2022Microbiology