Group A Streptococcus Induces Lysosomal Dysfunction in THP-1 Macrophages
S. T. Nishioka, J. Snipper, J. Lee, J. Schapiro, R. Z. Zhang, H. Abe, A. Till, C. Y. Okumura
This study shows Group A Streptococcus (GAS) persists in macrophages by inducing lysosomal dysfunction through membrane perforation and blocking acidification.
bioRxiv · Jun 17, 2022 · PreprintMicrobiology