The diagnostic chronic lymphocytic leukaemia genome by nanopore sequencing
A. Burns, D. Disalvo-Williams, D. Bruce, P. Robbe, A. Timbs, B. Stamatopoulos, R. Clifford, M. Lopopolo, D. Parkes, K. Ridout, A. Schuh
This paper presents a nanopore-based assay for CLL diagnostics, showing it can detect TP53 mutations, del17p13.1, and IgHV status in one run with high accuracy.
bioRxiv · Aug 28, 2019 · PreprintCancer Biology