Author

A. Trkola

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:differential expression· 1 Organism:non-human primate· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

N. Friedrich· 2 shared A. Anagnostopoulos· 1 shared A. Ciuffi· 1 shared A. Hachfeld· 1 shared A. Rauch· 1 shared Alexander G. BickiD· 1 shared Alexandra CalmyiD· 1 shared Andri RauchiD· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

N. Friedrich

Author profile →

4 papers

Recent·Most cited

Increased CHIP Prevalence Amongst People Living with HIV

Alexander G. Bick, Konstantin Popadin, Christian W. Thorball, Md Mesbah Uddin, Markella V. Zanni, Bing Yu, Matthias Cavassini, Andri Rauch, Philip Tarr, Patrick Schmid, Enos Bernasconi, Huldrych F. Günthard, Peter Libby, Eric Boerwinkle, Paul J. McLaren, , S. Yerly

The paper investigates the prevalence of clonal hematopoiesis of indeterminate potential (CHIP) in people living with HIV and finds a higher prevalence compared to controls.

Scientific Reports · Jan 12, 2022Peer-reviewedGenetic & Genomic Medicine

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

C. Caillat, D. Guilligay, J. Torralba, N. Friedrich, J. L. Nieva, A. Trkola, C. Chipot, F. Dehez, W. Weissenhorn

This paper presents the crystal structure of HIV-1 gp41 in a fusion intermediate state, revealing conformational plasticity and how antibodies block membrane fusion.

bioRxiv · Nov 12, 2020Microbiology

SARS-CoV-2 Variants Reveal Features Critical for Replication in Primary Human Cells

M. O. Pohl, I. Busnadiego, V. Kufner, I. Glas, U. Karakus, S. Schmutz, M. Zaheri, I. Abela, A. Trkola, M. Huber, S. Stertz, B. G. Hale

This study identifies SARS-CoV-2 variants with distinct replication abilities in human and non-human cells, highlighting cell-specific replication features.

bioRxiv · Oct 22, 2020Microbiology

Development of a high-throughput bead based assay system to measure HIV-1 specific immune signatures in clinical samples

T. Liechti, C. Kadelka, H. Ebner, N. Friedrich, R. D. Kouyos, H. F. Gunthard, A. Trkola

This paper develops a high-throughput bead-based assay to measure HIV-1 specific immune signatures in clinical samples, demonstrating improved antigen reactivity and reproducibility.

bioRxiv · Sep 28, 2017Immunology