Reduction of a heme cofactor initiates N-nitroglycine degradation by NnlA
K. A. Strickland, A. A. Holland, A. Trudeau, I. Szlamkowicz, M. J. Beazley, V. A. Anagnostopoulos, D. E. Graham, J. D. Caranto
This study identifies NnlA as a heme-containing enzyme that requires heme reduction for N-nitroglycine degradation, showing non-heme FeII is not essential for activity.
bioRxiv · Jun 19, 2022Biochemistry