Bone Morphogenetic Protein (BMP) signaling upregulates expression of ID1 and ID3 in pancreatitis and pancreatic ductal adenocarcinoma
M. K. Raghunathan, K. M. Scully, A. Wehrmaker, R. Murad, A. M. Lowy, H. C. Maurer, K. E. DelGiorno, P. Itkin-Ansari
This study identifies BMP signaling as a driver of ID1 and ID3 upregulation in pancreatitis and PDAC, linking it to poor patient survival and disease progression.
bioRxiv · Sep 1, 2023 · PreprintCancer Biology