Viral hijacking of the nucleolar DNA-damage response machinery: a novel mechanism to regulate host cell biology
S. M. Rawlinson, T. Zhao, A. M. Rozario, C. L. Rootes, P. J. McMillan, A. W. Purcell, A. Woon, G. A. Marsh, K. G. Lieu, L.-F. Wang, H. J. Netter, T. D. Bell, C. R. Stewart, G. W. Moseley
The paper identifies a novel viral mechanism that hijacks the nucleolar DNA-damage response pathway by interacting with Treacle to inhibit rRNA biogenesis.
bioRxiv · Nov 17, 2017Microbiology