Parkin is not required to sustain OXPHOS function in adult mammalian tissues
R. Filograna, J. Gerlach, H.-N. Choi, G. Rigoni, M. Barbaro, M. Oscarson, S. Lee, K. Tiklova, M. Ringner, C. Koolmeister, R. Wibom, S. Riggare, I. Nennesmo, T. Perlmann, A. Wredenberg, , N.-G. Larsson
This study shows that PARKIN is not required for OXPHOS function in adult mammalian tissues, using mouse models and a patient with PARKIN deficiency.
bioRxiv · Sep 2, 2023Cell Biology