Profiling immunoglobulin repertoires across multiple human tissues by RNA Sequencing
S. Mangul, I. Mandric, H. T. Yang, N. Strauli, D. Montoya, J. Rotman, W. V. Der Wey, J. R. Ronas, B. Statz, A. Zelikovsky, R. Spreafico, S. Shifman, N. Zaitlen, M. Rossetti, K. M. Ansel, E. Eskin
The paper develops ImReP, a computational method to profile TCR and BCR repertoires from RNA-seq data, creating a large atlas of immunological sequences across 53 tissues.
bioRxiv · Nov 6, 2018 · PreprintImmunology