Rapid DNA Replication Origin Licensing Protects Stem Cell Pluripotency
J. P. Matson, R. Dumitru, P. Coryell, R. M. Baxley, W. Chen, K. Twaroski, B. R. Webber, J. Tolar, A.-K. Bielinsky, J. Purvis, J. G. Cook
This study shows that rapid DNA replication origin licensing in pluripotent stem cells maintains pluripotency by enabling fast MCM loading despite short G1 phases.
bioRxiv · Jul 17, 2017Cell Biology