Automated liquid handling extraction and rapid quantification of underivatized amino acids and tryptophan metabolites from human serum and plasma using dual-column U(H)PLC-MRM-MS and its application to prostate cancer study.
T. Kipura, M. Hotze, A. Hofer, A.-S. Egger, L. E. Timpen, C. Opitz, P. Townsend, L. Gethings, K. Thedieck, M. Kwiatkowski
The paper develops an automated workflow and dual-column U(H)PLC-MRM-MS method to rapidly quantify amino acids and tryptophan metabolites in human serum and plasma, applied to a prostate cancer study to identify biomarkers.
Metabolites · Jun 30, 2024Peer-reviewedBiochemistry