Author

S. Seifert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Zerial· 3 shared Y. Kalaidzidis· 3 shared U. Repnik· 2 shared A. C. Fagre· 1 shared A. Giner· 1 shared A. Gollowitzer· 1 shared A. Hendriks· 1 shared A. Kowar· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCell Biology

M. Zerial

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The MTORC1-AHR pathway sustains translation and autophagy in tumours under tryptophan stress

P. Holfelder, L. Hensen, M. T. Prentzell, P. Razquin Navas, M. Solvay, A. Sadik, D. Sayeeram, U. Rehbein, T. Bausbacher, A.-S. Egger, L. Regin, A. M. Heberle, S. Seifert, A. Leytens, A. Kowar, , S. Harder

This study identifies the MTORC1-AHR pathway as a mechanism sustaining translation and autophagy in tumors under tryptophan stress by enhancing AHR activity and autophagy regulators.

bioRxiv · Jan 16, 2023 · PreprintBiochemistry

The Global Virome in One Network (VIRION): an atlas of vertebrate-virus associations

C. J. Carlson, R. J. Gibb, G. F. Albery, L. Brierley, R. Connor, T. Dallas, E. A. Eskew, A. C. Fagre, M. J. Farrell, H. K. Frank, R. d. L. Muylaert, T. Poisot, A. Rasmussen, S. J. Ryan, S. Seifert

The paper creates VIRION, a comprehensive database of vertebrate-virus associations, and demonstrates its utility for studying microbiology, ecology, and evolution.

bioRxiv · Aug 6, 2021Microbiology

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

L. Belicova, U. Repnik, J. Delpierre, E. Gralinska, S. Seifert, J. I. Valenzuela, H. A. Morales-Navarrete, C. Franke, H. Raagel, E. Shcherbinina, T. P. Prikazchikova, V. Koteliansky, M. Vingron, Y. Kalaidzidis, T. Zatsepin, M. Zerial

This study identifies apical bulkheads in hepatocytes as mechanical structures that drive anisotropic lumen expansion during liver development.

Journal of Cell Biology · Jul 30, 2021Peer-reviewedCell Biology

The novel Rab5 effector FERRY links early endosomes with the translation machinery

J. S. Schuhmacher, S. tom Dieck, S. Christoforidis, C. Landerer, J. Davila Gallesio, L. Hersemann, S. Seifert, R. Schaefer, A. Giner, A. Toth-Petroczy, Y. Kalaidzidis, K. E. Bohnsack, M. T. Bohnsack, E. M. Schuman, M. Zerial

This study identifies FERRY as a Rab5 effector that localizes mRNAs and ribosomes to early endosomes, impacting mRNA distribution and causing brain damage when disrupted.

bioRxiv · Jun 20, 2021 · PreprintCell Biology

3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

F. Segovia-Miranda, H. Morales-Navarrete, M. Kucken, V. Moser, S. Seifert, U. Repnik, F. Rost, A. Hendriks, S. Hinz, C. Rocken, D. Luthjohann, Y. Kalaidzidis, C. Schafmayer, L. Brusch, J. Hampe, M. Zerial

This study creates 3D spatial models of human liver tissue to identify new morphometric parameters and topological defects linked to NAFLD progression.

bioRxiv · Mar 9, 2019Pathology