Author

A.M. McDermott

George Washington University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Aravind MeyyappaniD· 1 shared Ari Hoffman· 1 shared David MendelowitziD· 1 shared Erin C. JonesiD· 1 shared John R. BetheaiD· 1 shared Kayla L. NguyeniD· 1 shared Kelly TammeniD· 1 shared Maeva Talla· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Aravind MeyyappanORCID

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2 papers

Recent·Most cited

Impaired Myelination in Multiple Sclerosis Organoids: p21 Links Oligodendrocyte Dysfunction to Disease Subtype

Saud A. Sadiq, Tanmay Mehta, William Holzman, A.M. McDermott, Nicolas Daviaud

The paper uses MS patient-derived organoids to show impaired oligodendrocyte differentiation and myelination linked to p21 pathway dysregulation in PPMS.

Frontiers in Cellular Neuroscience · Mar 24, 2026Peer-reviewedNeuroscience

ER oxidoreductin-1α and unfolded protein response as sex-dependent drivers of cardiorenal dysfunction in experimental autoimmune encephalomyelitis

Kayla L. Nguyen, Kelly Tammen, A.M. McDermott, Sreejita Arnab, Ari Hoffman, Maeva Talla, Nikhil Agarwal, Erin C. Jones, Aravind Meyyappan, David Mendelowitz, Yair Argon, John R. Bethea

This study investigates sex-specific cardiorenal dysfunction in EAE, finding distinct ER stress/UPR alterations and sex-dependent therapeutic responses to ERO1 inhibition and IRE1 activation.

bioRxiv · Oct 6, 2025 · PreprintMolecular Biology