Aravind Meyyappan

This study shows that TNFR2 agonism can prevent and reverse OA-induced cardiac dysfunction in female mice and delay systolic decline in males, revealing sex-specific cardiac effects of OA.

This study shows that TNFR2 signaling in hippocampal Nex/Neurod6 neurons is critical for chronic neuropathic pain recovery, acting through sex-dependent opioid and endocannabinoid pathways.

This study characterizes a novel mouse model of OA-induced heart failure, revealing sex-specific cardiac remodeling and molecular pathways associated with different HF phenotypes.

This study investigates sex-specific cardiorenal dysfunction in EAE, finding distinct ER stress/UPR alterations and sex-dependent therapeutic responses to ERO1 inhibition and IRE1 activation.