Smooth Muscle Cell-Specific TGFβ2 Protects Against Thoracic Aortic Aneurysm and Dissection in Mice
Mengistu G. Gebere, Mrinmay Chakrabarti, John Johnson, Aamina Azhar, Xiaoqin Wang, Naren R. Vyavahare, Mohamad Azhar
This study shows that TGFβ2 from vascular smooth muscle cells is essential for aortic wall integrity, and its loss leads to aneurysms and dissection in mice.
bioRxiv · Oct 1, 2025 · PreprintCell Biology