C-terminal domain of the filamentous hemagglutinin FhaB is crucial for interaction of Bordetella pertussis with ciliated epithelial cells
David Jurnečka, Josef Chmelik, Jana Holubová, Ondřej Staněk, Petra Kasparova, Abdul Samad, Jana Prošková, Karolína Škopová, Markéta Dalecká, Dominik Pinkas, Peter Šebo, Christopher S. Hayes, Ladislav Bumba
This study identifies the C-terminal domain of FhaB as essential for Bordetella pertussis adhesion to ciliated epithelial cells and colonization, suggesting it as a candidate for improved vaccines.
bioRxiv · May 27, 2026 · PreprintMicrobiology