Meghan A. Morrissey

The paper shows that inhibitory Fc{gamma}RIIB limits macrophage signaling duration, while activating Fc receptors control sensitivity, using chimeric receptors and in silico modeling.

This study shows that the Bordetella FhaB protein's microtubule-binding domain is delivered into host cells to promote bacterial colonization by interacting with microtubules in cilia.

This study identifies SFPQ as a factor promoting homologous recombination by stabilizing RAD51 and its paralogs' mRNA, independent of DSB localization or p53 activation.

This study shows CD47 inhibits Rac-mediated phagocytosis by preventing Vav1 phosphorylation, shifting the mechanism from Rac-based reaching to Rho-based sinking.

This study shows that target cell adhesion limits macrophage phagocytosis and promotes trogocytosis, with reduced adhesion increasing phagocytosis.

This study shows that prior Fc receptor activation primes macrophages to be more sensitive to IgG, enhancing phagocytosis through short- and long-term mechanisms.

The paper identifies RNF146 and tankyrase as regulators of peroxisome function and links them to Wnt signaling through their role in PARsylation and beta-catenin degradation.

This study shows that overexpressing Aquaporin-1 in diverse cell lines does not harm cell viability or function, making it a safe tool for magnetic resonance imaging.